Cleanroom Engineering ISO 1–8 / GMP
Overview 4-Stage Pipeline Airflow Loop ACH Calculator
Consult Engineer
ISO 14644-1 Class 1–8 • EU GMP Grade A/B • Zero Outgassing

Submicron particle control down to 0.1 µm. Guaranteed fab yield.

From advanced semiconductor wafer bumping and photolithography in Penang and Kulim to sterile pharmaceutical injectable fill-lines: Superado Gel-Seal H14 / U15 HEPA filters and low-energy ePTFE membrane media deliver ISO Class 1 to Class 5 laminar purity without gasket bypass risks.

Calculate Cleanroom ACH ROI → Explore 4-Stage Airflow Loop
99.9995%
EN 1822 U15 ULPA Efficiency
Captures submicron particles at Most Penetrating Particle Size (MPPS 0.12 μm) with zero pinhole leaks.
0.45 m/s
Unidirectional Laminar Flow
Maintains ±15% face velocity uniformity across ceiling T-grid modules, satisfying GMP Grade A aseptic requirements.
< 0.01%
PAO Scan Leakage Limit
In-situ aerosol photometer leak testing verified on-site in accordance with ISO 14644-3 and IEST-RP-CC002.
40% Lower
Fan Energy Consumption
SuperPTFE™ membrane media operates at 85 Pa initial resistance vs 140 Pa for microglass, slashing 24/7 power draw.
Semiconductor & Pharma Risk Analysis

The three critical failure modes in high-tech cleanrooms.

In nanometer-scale semiconductor fabrication and sterile pharmaceutical compounding, a single aerosol bypass incident halts entire multi-million ringgit production lines.

Boron & AMC Outgassing Contamination

Conventional micro-fiberglass filter media utilizes organic binders that off-gas trace boron, phosphorus, and volatile siloxanes under continuous airflow. In sub-14nm wafer photolithography, airborne boron deposits onto silicon surfaces, creating wafer haze and catastrophic integrated circuit bridging defects.

Superado Solution: SuperPTFE™ ePTFE membrane media with thermally bonded fluoropolymer fibers contains zero boron and zero organic chemical outgassing.

Gasket Degradation & Bypass Leakage

Traditional closed-cell neoprene and EPDM mechanical gaskets suffer from uneven compression torque across ceiling grids. Over 18 months, gasket shrinkage allows microscopic air bypass around the frame. In sterile pharma fill suites, this allows bacterial spores (0.2 µm) to breach Grade A containment.

Superado Solution: SuperSeal™ Gel-Seal fluid urethane channels embed the ceiling knife-edge grid with 100% airtight sealing that never loses elastic memory.

Massive 24/7 FFU Electrical Utility Drag

Operating 800 to 2,500 Fan Filter Units (FFUs) in a 24/7/365 semiconductor fab against dense, high-resistance fiberglass filters consumes hundreds of thousands of kilowatt-hours. Standard filters operate at 140–180 Pa, generating excessive motor heat that forces chiller plants to work overtime.

Superado Solution: Ultra-thin ePTFE micro-pores reduce clean filter resistance to 85 Pa, cutting annual FFU electrical operating expense by over RM 100,000 per facility.
Cascading Airflow Architecture

The 4-stage recirculating cleanroom filtration loop.

Designed to maintain cascading positive room pressure (+15 to +25 Pa) and protect terminal HEPA/ULPA filters from premature particle loading.

Stage 01 • Make-Up Air (MAU)

Synthetic Pre-Filter Rolls

SuperRoll™ G4 Washable + SuperPocket™ M6

Arrests outdoor tropical dust, pollen, and airborne soot at the fresh air intake louvers, protecting chilled water cooling coils and humidification chambers.

Arrestance: ISO Coarse 80% • EN 779 G4
Clean Resistance: 40 Pa Initial DP
Stage 02 • Recirculation (RAU)

High-Surface 4V Mini-Pleat

SuperVee™ F9 / E11 Mini-Pleat Banks

Captures 95% of fine submicron particles (PM1) in the recirculating plenum. Prevents rapid loading of expensive ceiling HEPA units, extending terminal filter life to 6+ years.

Efficiency: ISO ePM1 90% • EN 779 F9
Media Area: 18 m² Extended Surface
Stage 03 • Terminal Ceiling Grid

Gel-Seal Knife-Edge HEPA

SuperSeal™ H14 Mini-Pleat Gel (99.995%)

High-efficiency terminal ceiling filter with anodized aluminum knife-edge channel and polyurethane blue gel. Self-healing fluid seal guarantees zero bypass leakage into cleanrooms.

Efficiency: 99.995% at MPPS (0.12μm)
Seal Integrity: 100% Knife-Edge Fluid Seal
Stage 04 • Photolithography Zone

Low-Boron PTFE ULPA U15

SuperPTFE™ Semiconductor Membrane

Engineered for sub-10nm wafer fabrication and sterile pharmaceutical compounding. Zero chemical outgassing, high tensile strength, and 40% lower initial operating pressure drop.

Efficiency: 99.9995% at 0.12μm (ULPA U15)
Chemical Outgassing: Non-Detectable (ND)
Cleanroom Fluid Dynamics • ISO 14644-1

Laminar recirculation cleanroom loop architecture.

Full cross-sectional flow engineering from ceiling Fan Filter Units (FFU) through unidirectional downflow clean zones, perforated raised access flooring, and return air plenums.

ISO Class 1 to Class 5 Semiconductor Cleanroom Airflow Loop

Ceiling Gel-Seal FFU matrix with 0.45 m/s downward laminar velocity and raised floor return circulation.

ISO 14644-1 & GMP Grade A Blueprint
ISO CLASS 4 / 5 POSITIVE PRESSURE RECIRCULATION ROOM (+20 PA) CEILING PRESSURE PLENUM (SUPPLY FROM RAU) FFU 01 (H14) FFU 02 (U15) FFU 03 (U15) FFU 04 (H14) SUPERSEAL™ KNIFE-EDGE BLUE GEL SEAL CHANNEL WAFER TRACK / PHOTO CLUSTER 300mm WAFER PERFORATED ACCESS FLOOR (25% OPEN AREA) UNDERFLOOR RETURN AIR PASSAGE TO RECIRCULATION RISERS 0.45 M/S UNIDIRECTIONAL LAMINAR CLEAN DOWNFLOW
Microelectronics semiconductor wafer cleanroom in Malaysia
Semiconductor Fab Cleanroom: ISO Class 1 to Class 5 wafer photolithography clean zone operating with SuperSeal™ Gel-Seal HEPA and low-boron ULPA ceiling arrays.
Cleanroom validation engineer conducting PAO aerosol photometer leak scan on ceiling HEPA unit in Penang
In-Situ PAO Leak Validation: Certified validation engineer in sterile bunny suit scanning knife-edge ceiling HEPA frame with isokinetic aerosol photometer probe in Penang.
Cleanroom Performance Benchmarking

Standard fiberglass HEPA vs. SuperSeal™ & SuperPTFE™.

Compare chemical outgassing, frame sealing reliability, and long-term 24/7 fan operating energy across high-tech cleanroom filter technologies.

Cleanroom Performance Parameter Standard Microglass HEPA (Gasket) SuperSeal™ Gel-Seal H14 SuperPTFE™ Low-Energy ULPA U15
Frame Sealing Mechanism
Seal integrity against ceiling T-grid 		Neoprene Gasket (Torque Dependent) Knife-Edge Polyurethane Blue Gel Knife-Edge Gel or Dry Knife-Edge
Chemical Outgassing (AMC)
Boron, Phosphates, Volatile Siloxanes 		Significant Boron Release (> 50 ng/m³) Low Outgassing Binder Zero Boron / Zero AMC Outgassing
Initial Pressure Resistance
Clean pressure drop at 0.45 m/s face velocity 		135 – 160 Pa (High Energy Draw) 110 – 125 Pa 75 – 85 Pa (40% Energy Savings)
Mechanical Media Fragility
Resistance to fiber tearing during installation 		Fragile (Easily punctured by touch) Protected by Painted Faceguards High Tensile Strength ePTFE Membrane
On-Site PAO Aerosol Scan Pass Rate
ISO 14644-3 Leak Scanning < 0.01% 		88% (Frequent edge leak retorquing) 100% First-Time Pass 100% First-Time Pass (Zero Pinholes)
Malaysian High-Tech Track Record

Field outcomes across Bayan Lepas, Kulim & Bandar Enstek.

Real operations where semiconductor wafer fabs, medical device plants, and sterile pharmaceutical producers eliminated yield defect losses, reduced fan power, and passed stringent audits.

Bayan Lepas FTZ, Penang • Advanced Wafer Bumping

Zero-Boron ULPA Retrofit for Sub-14nm Packaging

The Problem: Advanced 3D wafer packaging line suffered chronic surface haze defects during copper pillar electroplating. Chemical gas analysis traced the defect to boron outgassing from standard microglass ceiling HEPA filters, causing a 3.8% die yield loss.
Superado Solution: Full ceiling retrofit with SuperPTFE™ U15 ULPA low-boron membrane modules with gel-seal knife-edge framing, pre-tested to EN 1822 with individual serial certification.
Verified Result: Airborne boron concentration dropped below detection limits (< 0.1 ng/m³); wafer die yield increased to 99.85%. Saved RM 840,000 annually in defect prevention.
Kulim Hi-Tech Park (KHTP), Kedah • 300mm Power Fab

40% Cleanroom FFU Fan Energy Reduction

The Problem: A 2,200 m² cleanroom operating 650 ceiling FFUs faced spiraling electricity bills. Existing fiberglass HEPA units operated at 155 Pa static resistance, overloading FFU blowers and generating excess heat into the cleanroom.
Superado Solution: Replacement with SuperPTFE™ Ultra-Low Energy U15 filters operating at only 82 Pa initial resistance at 0.45 m/s, backed by high-capacity SuperVee™ F9 recirculation pre-filters.
Verified Result: Cleanroom fan static power dropped by 38%, saving 245,000 kWh annually (RM 115,000/year) in electricity while maintaining pristine ISO Class 4 cleanliness.
Bandar Enstek, N.S. • Sterile Pharma Injectables

GMP Annex 1 Grade A First-Pass Sterility Certification

The Problem: Aseptic vial filling line faced recurrent gasket air bypass during NPRA / PIC/S regulatory audits. Re-tightening mechanical gasket clamps caused frame distortion and temporary stop-production notices.
Superado Solution: Installed SuperSeal™ Gel-Seal H14 (99.995%) terminal ceiling hood modules with self-healing blue urethane fluid seals and integral aerosol injection ports.
Verified Result: 100% first-pass PAO aerosol scan approval across 180 terminal hoods. Zero microbial colony forming units (CFU = 0) recorded during 24-month environmental monitoring.
Interactive Cleanroom Engineering Tool

Calculate cleanroom airflow, FFU count & fan energy ROI.

Input your cleanroom dimensions and target ISO class to compute required Air Changes per Hour (ACH), necessary Fan Filter Units (FFU), and projected annual electrical savings with low-energy SuperPTFE™ media.

Cleanroom Facility Operating Parameters

Adjust the sliders to model your semiconductor or pharmaceutical cleanroom:

Cleanroom Floor Area (m²): 150 m²
Ceiling Clear Height (m): 3.0 m
Projected Annual Fan Electricity Savings
RM 29,800
Saving ~60 Pa static resistance operating 24/7/365 across ceiling FFUs.
113 FFUs
Recommended FFUs (4ft × 2ft)
135,000 m³/h
Total Recirculation Airflow
Request PAO Validation & Engineering Audit
Cleanroom Engineering Advisory

Schedule an on-site cleanroom validation & filter integrity audit.

Our NEBB / IEST-certified cleanroom engineers conduct on-site aerosol photometer PAO leak testing, anemometer velocity profile mapping, room pressure cascading audits, and low-boron filtration retrofits.

EN 1822 Individual Serial Test Certificates included with all HEPA/ULPAs
Zero-Boron ePTFE Membrane Media in stock in Puchong & Penang
Full ISO 14644-3 & GMP Validation Dossier calibration reports
Cleanroom Technical Validation Hotline
+60 3-8070 8822
Mon – Fri: 8:30 AM – 6:00 PM | Puchong Headquarters • Penang On-Site Team